About Me

My name is Enes Kemal. I'm a computational biologist and bioinformatician — I recently completed my PhD in Bioinformatics at UBC, and I now work as a Staff Bioinformatician in the Lange Lab at BC Children's Hospital Research Institute.

My research centers on proteomics and pediatric cancer. What draws me to this work is how meaningful it is — developing rigorous computational methods for childhood cancer research is both scientifically rich and genuinely impactful. My doctoral work focused on proteoform-level analysis in bottom-up mass spectrometry data: building statistical frameworks for equivalence testing, improving peptide-level quantification, and identifying dysregulated proteoforms in pediatric tumours.

I also love building things. Whether it's a full proteomics analysis platform or a fast FASTA indexer in Zig, I care about performance, clean design, and tools that scientists actually want to use. That blend of rigorous research and a builder's mindset is what keeps me going.

Latest News

  • [Feb 2026] Open-sourced z-fasta, an ultra-fast FASTA indexer written in Zig.
  • [Dec 2025] Submitted third paper, ProteoForge, to bioRxiv; currently under revision for the Journal of Proteome Research. bioRxiv preprint
  • [Apr 2025] Successfully defended PhD dissertation without revisions; thesis deposited to cIRcle at UBC.
  • [Apr 2025] Fifth co-authored paper (PROFYLE) published in EMBO Molecular Medicine.
  • [May 2024] Published second first-authored paper on QuEStVar in the Journal of Proteome Research.
  • [Nov 2023] Fourth co-authored paper, led by Dr. Amanda Lorentzian, published in Nature Communications.
  • See all news →

Work Experience

BC Children's Hospital Research Institute

Lange Lab — Vancouver, BC

Staff Bioinformatician June 2025 – Present

  • Continuing proteomics method development and maintaining active research projects in childhood cancer genomics and proteomics.

Graduate Research Assistant September 2017 – April 2025

  • Research: Developed statistical and computational methods for exploring proteomic features in childhood cancers using bottom-up mass spectrometry data, with a focus on proteoforms. PhD Thesis
  • Aim 1: Expand statistical explainability in proteomics through equivalence testing — QuEStVar (Journal of Proteome Research, 2024)
  • Aim 2: Improve peptide-level identification and quantification in proteomics data — SQuAPP (Oxford Bioinformatics, 2022)
  • Aim 3: Identify quantitatively distinct proteoforms at the peptide level in Neuroblastoma — ProteoForge (under revision, 2025)
BCCHR logo

Computational Finance Lab at NAU

Research Assistant Houston, TX January 2017 - May 2017

NAU Logo

Department of Computer Science

Teaching AssistantHouston, TX September 2015 - May 2017

NAU Logo

Department of Genetics

Visiting Researcher Boston, MA November 2015 - September 2016

HMS Logo

Bioinformatics Lab at NAU

Student Leader Houston, TX September 2015 - May 2017

bv_logo

Association for Computing Machinery at NAU

Organization OfficerHouston, TXSeptember 2013 - May 2017

ACM NAU Logo

Department of Genetics and Bioengineering

Undergraduate Research Assistant Istanbul, Turkey August 2014 - May 2015

Yeditepe Logo

Harmony Public Schools

Software Development Intern Houston, TXJanuary 2015 - August 2015

HPS Logo

Education

UBC Logo

University of British Columbia

Doctor of Philosophy in Bioinformatics Vancouver, BC 2019 – 2025

Master of Science in Bioinformatics Vancouver, BC 2017 – 2019 (Transferred to PhD)

  • Advisor: Philipp F. Lange
  • Thesis: “Computational interrogation of proteoform dynamics in pediatric cancer”
  • Research: Statistical and computational methods for proteoform-level analysis of bottom-up MS data in childhood cancer, with focus on equivalence testing, peptide quantification, and proteoform discovery.
uiuc_logo

North American University

Bachelor of Science in Computer Science Houston, TX September 2013 - May 2017

  • Graduated with Distinction.
  • Specialized on Bioinformatics
  • Served as Parlimentarian at Student Government for 3 years
  • Lab Lead of Bioinformatics Lab
  • Lab lead of Computational Finance Lab
  • Served as Director at Future Leaders Clup
mooc_logo

Online Certifications

Motivated Self-learner Houston, TX August 2012 - Present