tag: quantification
2 posts, 2 projects, 3 publicationsWriting about quantification from May 2020 to December 2025.
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The story behind ProteoForge, a framework for finding differential proteoforms in bottom-up proteomics data. Why protein-level averages hide biology, how missing data broke every tool we tried, and what we found when we applied it to a hypoxia dataset.
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reading
proDA
Probabilistic dropout analysis for label-free proteomics. Handles missing values by modeling dropout curves instead of imputing.